Experience of Antibiotic Use and Resistance Among Pharmacy Students in the University of Kerbala

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Ahmed Sahib
Saif Abbas
Karar Hasson
Mohammed Mahmoud


Antibiotic resistance occurs when bacteria develop the ability to defeat the drugs designed to kill them. Antibiotics dispensing without prescription, misuse of antibiotics are considered as a major cause of antibiotic resistance. Antimicrobial resistance causes extra health care cost and leads to loss of productivity; also patients with resistant infections are more expensive and difficult to treat. Many strategies and steps can be taken at all levels of society to reduce the impact and limit the spread of resistance. The pharmacist has effective role in averting antibiotic resistance. Methodology: A questioner form was designed to assess student’s knowledge, attitude and perception about antibiotic use and resistance, 146 pharmacy students from the fourth stage and fifth stage in the University of Kerbala, were selected randomly. Result: A total number of 146 students, (70 from the fourth stage and 76 from the fifth stage) were participated in this study of both sexes (30 male: 116 female). About 82% of students understand what the antibiotic resistance term mean. 87% of students knew that antibiotics shouldn’t be used for common cold. 84% of students did not stop taking antibiotics until taken all of the antibiotics as directed. 34% of students usually consult a doctor before starting an antibiotic. Less than 23% of students did not stop taking antibiotic when any side effect appears. Conclusion: Based on results obtained in this study that done in Kerbala University / College of Pharmacy it has been concluded that students were of high level in knowledge and perception about antibiotics use and resistance, but the students were of lower level in attitudes, lower percent of student have good attitude toward antibiotics use.


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Abboud, M. M., Saeed, H. A., Tarawneh, K. A., Khleifat, K. M., & Al Tarawneh, A. (2009). Copper uptake by Pseudomonas aeruginosa isolated from infected burn patients. Current microbiology, 59(3), 282-287.

Ahmed A, Umair M, Patel I, Maharaj S, Pandey S (2015) knowledge, attitude and practice of B.Sc pharmacy students about antibiotics in Trinidad and Tobago. Journal of research in pharmacy practice,4(1):1-5.

Al-Asoufi, A., Khlaifat, A., Tarawneh, A., Alsharafa, K., Al-Limoun, M., & Khleifat, K. (2017). Bacterial quality of urinary tract infections in diabetic and non-diabetics of the population of Ma'an Province, Jordan. Pakistan J Biol Sci, 20, 179-88.

Althunibat, O. Y., Qaralleh, H., Al-Dalin, S. Y. A., Abboud, M., Khleifat, K., Majali, I. S., & Jaafraa, A. (2016). Effect of thymol and carvacrol, the major components of Thymus capitatus on the growth of Pseudomonas aeruginosa. J Pure Appl Microbiol, 10, 367-74.

BPACNZ: Antibiotics: the future is short. (https://bpac.org.nz/2018/antibiotics.aspx), Date of access. February-19-2019.

CDC: Antibiotic resistance questions and answers. (https://www.cdc.gov/antibiotic-use/community/about/antibiotic-resistance-faqs.html), Date of access. February-10-2019.

CDC: Antibiotic/Antimicrobial Resistance. (https:/ www.cdc.gov/ drugresistance/index.html), Date of access. July-18-2018.

CDC: Common cold and runny nose. (https://www.cdc.gov/antibiotic-use/community/for-patients/common-illnesses/colds.html), Date of access. February-17-2019.

CDC: Sore throat. (https://www.cdc.gov/antibiotic-use/community/for-patients/common-illnesses/sore throat.html?fbclid=IwAR2AvCNxlaKxvfxGh3bMQ0pKj33BZxVNfovYYwIGyof EDOpIemraNg36jIg), Date of access. February-20-2019.

Drugs: Common side effects from antibiotics, and allergies and reactions. (https://www.drugs.com/article/antibiotic-sideeffects-allergies-reactions.html), Date of access. February-27-2019.

Al-Zarea, E. A., Al-Sharari, A. O., Al-Zarea, N. I., & Taher, I. A. (2016). Knowledge, Attitudes and Practices of Antibiotics Usage among Health Sciences Students at Aljouf University, Saudi Arabia. Aljouf University Medical Journal, 300(5765), 1-10.

FDA: Antibiotics and Antibiotic Resistance. (https://www.fda.gov/ Drugs/ Resources For You/Consumers/Buying Using Medicine Safely /Antibioticsand AntibioticResistance/default.htm), Date of access. July-18-2018.

FDA: Combating Antibiotic Resistance. (https://www.fda.gov/ForConsumers/ConsumerUpdates/ucm092810.htm), Date of access. February-26-2019.

IDSA: Faces of antimicrobial resistance. (http://www.idsociety.org/uploadedFiles/ IDSA/FOAR/FOAR%20Report%201-up%20final.pdf), Date of access. June-15-2018.

Israa, N. (2017) knowledge of antibiotic use and resistance: A questionnaire study among 100 iraqi undergraduate pharmacy students. international journal of advanced research, 5(9): 1-12.

Khan, A. A., & Banu, G. K. K. R. (2013). Antibiotic Resistance and Usage-A Survey on the Knowledge, Attitude, Perceptions and Practices among the Medical Students of a Southern Indian Teaching Hospital. Journal of clinical and diagnostic research: JCDR, 7(8), 1613-1616.

Khleifat, K., Abboud, M., Al-Shamayleh, W., Jiries, A., & Tarawneh, K. (2006). Effect of chlorination treatment on gram negative bacterial composition of recycled wastewater. Pak. J. Biol. Sci, 9, 1660-1668.

Khleifat, K. M., Matar, S. A., Jaafreh, M., Qaralleh, H., Al-limoun, M. O., & Alsharafa, K. Y. (2019). Essential Oil of Centaurea damascena Aerial Parts, Antibacterial and Synergistic Effect. Journal of Essential Oil Bearing Plants, 22(2), 356-367.

Kulsoom, T., Iqra, S., Fatima, M., Hasnain, A., Shahid Imran, T., Hussnain, G. (2017) Knowledge and Perceptions of Medical Students Regarding Antibiotic Use. PJJMHS, 11(1): 1-5.

Abbo, L. M., Cosgrove, S. E., Pottinger, P. S., Pereyra, M., Sinkowitz-Cochran, R., Srinivasan, A., ... & Hooton, T. M. (2013). Medical students’ perceptions and knowledge about antimicrobial stewardship: how are we educating our future prescribers?. Clinical infectious diseases, 57(5), 631-638.

Majali, I. S., Oran, S. A., Khaled, M. K., Qaralleh, H., Rayyan, W. A., & Althunibat, O. Y. (2015). Assessment of the antibacterial effects of Moringa peregrina extracts. African Journal of microbiology research, 9(51), 2410-2414.

Mayo clinic: Fever. (https://www.mayoclinic.org/diseases-conditions/fever/diagnosis-treatment/drc-20352764), Date of access. February-19-2019.

NCBI: Antimicrobials including antibiotics, antiseptics and antifungal agents . (https://www.ncbi.nlm.nih.gov/books/NBK363143/), Date of access. March-5-2019.

NCBI: Using medication: Using antibiotics correctly and avoiding resistance. (https://www.ncbi.nlm.nih.gov/books/NBK361005/), Date of access. February-27-2019.

NZWCS: Should you complete an antibiotic course or stop when better. (https://www.nzwcs.org.nz/images/conferences/2017_Conference/Antibiotic - duration-NZWCSConf2017-DrREverts.pdf), Date of access. February-20-2019.

Ogunshe A, Adinmonyema P (2014) Evaluation of bacteriostatic potency of expired oral paediatric antibiotics and implications on infant health. Pan African medical journal, 19(378): 1-11.

Padmanabha T, Nandini T, Manu G, Madhav K, Shankar R (2016) knowledge, attitude and practices of antibiotic usage among the medical undergraduate of a tertiary care teaching hospital: and observational cross- sectional study. International journal of basic and clinical pharmacology, 5(6):1-6.

Qaralleh, H. N., Abboud, M. M., Khleifat, K. M., Tarawneh, K. A., & Althunibat, O. Y. (2009). Antibacterial activity in vitro of Thymus capitatus from Jordan. Pakistan journal of pharmaceutical sciences, 22(3).

Qaralleh, H., Idid, S., Saad, S., Susanti, D., Taher, M., & Khleifat, K. (2010). Antifungal and antibacterial activities of four Malaysian sponge species (Petrosiidae). Journal de Mycologie Médicale, 20(4), 315-320.

Qaralleh, H., Khleifat, K. M., Al-Limoun, M. O., Alzedaneen, F. Y., & Al-Tawarah, N. (2019). Antibacterial and synergistic effect of biosynthesized silver nanoparticles using the fungi Tritirachium oryzae W5H with essential oil of Centaurea damascena to enhance conventional antibiotics activity. Advances in Natural Sciences: Nanoscience and Nanotechnology, 10(2), 025016.

Qaralleh, H. N. (2018). Chemical composition and antibacterial activity of Origanum ramonense essential oil on the ?-lactamase and extended-spectrum ?-lactamase urinary tract isolates. Bangladesh Journal of Pharmacology, 13(3), 280-286.

Kanagal, D. V., Rajesh, A., Rao, K., Devi, U. H., Shetty, H., Kumari, S., & Shetty, P. K. (2014). Levels of serum calcium and magnesium in pre-eclamptic and normal pregnancy: A study from Coastal India. Journal of clinical and diagnostic research: JCDR, 8(7), OC01.

S. J. Hopkins (1997). Drugs and Pharmacology for Nurses (12th ed.). Churchill Livingstone.

Sakeena, M. H. F., Bennett, A. A., Jamshed, S., Mohamed, F., Herath, D. R., Gawarammana, I., & McLachlan, A. J. (2018). Investigating knowledge regarding antibiotics and antimicrobial resistance among pharmacy students in Sri Lankan universities. BMC infectious diseases, 18(1), 1-11.

Shazia, Q., Ramadan, E., Kingston, R., Abdul Kareem, A., Siti, H., Mohammad, J., Mohamad, A., Muhammad, B., Najwa, I., Mohammad, S., Nasrul, H., Normunirah, B., Nur, H., Nuratiqah, H., Nurul, A., Radhiyah, I., Siti, M. (2014) Understanding of antibiotic use and resistance among final-year pharmacy and medical students: a pilot study. The journal of infection in developing countries, 8(6): 1-6.

Tarawneh, K. A., Halasah, Z. A., Khleifat, A. M., Batarseh, M. I., Khleifat, K. M., & Al-Mustafa, A. H. (2011). Evaluation of cefaclor oral suspensions stability using reversed phase high performance liquid chromatography and antimicrobial diffusion methods. Pakistan journal of pharmaceutical sciences, 24(3).

WHO, WIPO, WTO: Antimicrobial resistance – a global epidemic. (https://www.wto.org/english/news_e/news16_e/heal_29aug16_e.pdf), Date of access. June-20-2018.

WHO: Global action plan on antimicrobial resistance. (http://www.wpro. who.int/entity/drug_resistance/resources/global_action_plan_eng.pdf), Date of access. June-22-2018.

WHO: The role of pharmacist in encouraging prudent use of antibiotic and averting antimicrobial resistance: a review of policy and experience. (http://apps.who.int/medicinedocs/documents/s22244en/s22244en.pdf), Date of access. June-24-2018.

Ying, H., Jiarui, G., Mingyu, Z., Zheng, R., Weidong, Y., Yang, C., Yingmei, F., Xiobei, C., Jochen, W. Cals and Fengmin, Z. (2016) Knowledge, attitude and practice of antibiotics: a questionnaire study among 2500 Chinese students. BMC medical education, 13(163): 1 – 9.

Zeidan, R., Oran, S., Khleifat, K., & Matar, S. (2013). Antimicrobial activity of leaf and fruit extracts of Jordanian Rubus sanguineus Friv. (Rosaceae). African Journal of Microbiology Research, 7(44), 5114-5118.